The Effect of Cigarette Smoke Exposure to The Number of Implantation Points in Pregnancy Mice (Mouse muscle)

Ayu Kusuma Wardani; Desi Kusumawati; Cicilia Novi Primiani

The Effect of Cigarette Smoke Exposure to The Number of Implantation Points in Pregnancy Mice (Mouse muscle)

Authors

Ayu Kusuma Wardani , Desi Kusumawati , Cicilia Novi Primiani

Published:

2025-08-01

Issue:

Vol. 1 No. 1 (2025): August

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Wardani, A. K., Kusumawati, D., & Primiani, C. N. (2025). The Effect of Cigarette Smoke Exposure to The Number of Implantation Points in Pregnancy Mice (Mouse muscle). NATURA: JURNAL ILMU ALAM DAN SOSIAL, 1(1), 25–30. Retrieved from https://jsss.lombokinstitute.com/index.php/natura/article/view/5

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Abstract

Implantation is the process by which the blastocyst sinks into the endometrium after the release of the Zona Pellucida. This study aims to examine the effect of cigarette smoke on the number of implantation points in pregnant mice (Mouse muscle). This study used a completely randomized design (CRD), with strained female mice as experimental animals Bal b/c species Mouse muscle two months old, totalling 24 tails. Treatment was given on day 1 of pregnancy with control treatment (P0), one cigarette (P1), and two cigarettes (P2). Surgery was performed on the 13th day to calculate the number of implantation points. Data were analyzed using One-Way ANOVA. The results showed the treatment's effect on the number of mice pregnancy implantation points (p < .05). Treatment P0 had the highest point of implantation, followed by treatments P1 and P2. These results indicate that cigarette smoke can inhibit the process of cell division, inhibit the formation and development of blastocysts, and further process pre-implantation and implantation in mice.

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The Effect of Cigarette Smoke Exposure to The Number of Implantation Points in Pregnancy Mice (Mouse muscle)

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