The Effect of Cigarette Smoke on The Weight of Mice Ovariums (Mouse muscle)

Abstract

This study aims to examine the effect of cigarette smoke on the weight of the mice's ovaries (Mouse muscle). The study used an experimental approach, with experimental female mice strains Balb/c species Mouse muscle aged 2-3 months totalling 24 pregnant tails. Mice were treated with cigarette smoke using an injection where the tip was cut so that there was a hole where the cigarette was burned once a day every morning or evening for 13 days. The treatment used three doses, namely P0 (0 cigarettes), P1 (1 cigarette), and P2 (2 cigarettes). Ovarian organ harvesting was carried out on the 13th day, followed by weighing the ovaries. The data obtained were then analyzed using One Way ANOVA. The results showed that (a) exposure to cigarette smoke did not have a significant effect on the weight of the mice's ovaries (Mouse muscle) during pregnancy, and (b) exposure to cigarette smoke significantly affects the number of follicles in the ovaries.